Fig. 9
From: Flexible selection of diversified Na+/K+-ATPase α-subunit isoforms for osmoregulation in teleosts
Evolutionary scheme of NKA α-subunit in teleosts with various strategies adopted by different lineages. Multiple α1 isoforms/transcripts were generated by tandem gene duplication, gene fusion, alternative splicing. The α1a and α1b among different species are non-monophyletic and were generated via different lineage-specific duplication events. The isoform composition (pink shaded) indicates the hypothetical condition before divergence of different teleost lineages. Known changes in gene expression in known organs (indicated by colored dotted arrows) during salinity transfer are shown in different colors. Red dotted arrow = gill-specific; orange dotted arrow = intestine-specific; black dotted arrow = kidney-specific. 3RWGD = teleost specific 3rd round whole genome duplication