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Table 1 Efficacy of typical ROR ligands in mammals for medaka RORd1

From: A fourth subtype of retinoic acid receptor-related orphan receptors is activated by oxidized all-trans retinoic acid in medaka (Oryzias latipes)

Ligand

Efficacy against EtOH (%)

20α-hydroxycholesterol

1.57 ± 0.06

7α-hydroxycholesterol

1.25 ± 0.01

7β-hydroxycholesterol

1.22 ± 0.00

7-ketocholesterol

1.27 ± 0.06

cholesterol

ND

22R–hydroxycholesterol

ND

25-hydroxycholesterol

1.55 ± 0.11

  1. ND not detected
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Zoological Letters

ISSN: 2056-306X

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