Fig. 1

Hgf and Met expressions in mouse embryos. Hgf (a, b) and Met (g, h) expression pattern in mouse embryos at E10 (a, c) and E10.25 (b, d) stages. Lateral views. Transverse sections of E10.25 embryos after in situ hybridization with Hgf (c-f) and Met (i-l) probes. The dorsal pericardial region in (i) is magnified in (j). Section levels are indicated in (b) and (h). Note that Hgf is expressed in the migration route of HBM precursors, and also in the dorsal and ventral part of forelimb bud. Met expression was found in HBM and FLM precursors. aa, arch artery; ccv, common cardinal vein; da, dorsal aorta; ddm, dorsal part of dermomyotome; dm, dermomyotome; fl, forelimb bud; FLMp, forelimb muscle precursors; HBMp, hypobranchial muscle precursors; hy, hyoid arch; li, liver anlage; ma, mandibular arch; ne, nasal epithelium; nt, neural tube; oft, outflow tract; pa3, third pharyngeal arch; pa4, fourth pharyngeal arch; pe, pharyngeal endoderm; ph, pharynx; ra, right atrium; tHBM, trajectory of hypobranchial muscle; vdm, ventral part of dermomyotome. Scale bars on whole embryos, 200 μm. Scale bars on sections, 50 μm