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Fig. 3 | Zoological Letters

Fig. 3

From: Stepwise participation of HGF/MET signaling in the development of migratory muscle precursors during vertebrate evolution

Fig. 3

Hgf and Met expressions in shark embryos. Hgf (a–h) and Met (i–l) expression patterns in S. torazame embryos at stage 25 (a, b, i and j) and 27 (c–h, k and l). Lateral views of rostral (a, c, i and k) and caudal (b, d, j and l) parts of the embryos. Transverse sections of stage 27 embryos after in situ hybridization with Hgf probe (e–h). Section levels are indicated in (c). Shark Hgf is expressed in the posterior portion of fin buds, but not in the migration route of HBM precursors. Met expression was transiently detected in the ventral part of dermomyotome at stage 25, but not in the HBM and fin muscle precursors at stage 27. acv, anterior cardinal vein; ccv, common cardinal vein; cl, cloaca; cv, caudal vein; fb, forebrain; gb, gill buds; hc, head cavities; hy, hyoid arch; hyp, neurohypophysis; ma, mandibular arch; mcv, mesenchyme lateral to the cardinal vein; nt, neural tube; os, optic stalk; ot, otic vesicle; pa3, third pharyngeal arch; pa7, seventh pharyngeal arch; pcm, pericardium; pf, pectoral fin bud; PFMp, pectoral fin muscle precursors; plf, pelvic fin bud; pom, periocular mesenchyme; vdm, ventral dermomyotome; V, trigeminal nerve; VII, facial nerve; VIII, vestibulocochlear nerve; IX, glossopharyngeal nerve; X, vagus nerve. Scale bars on whole embryos, 200 μm. Scale bars on sections, 50 μm

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