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Fig. 5 | Zoological Letters

Fig. 5

From: Stepwise participation of HGF/MET signaling in the development of migratory muscle precursors during vertebrate evolution

Fig. 5

Stepwise participation of HGF/MET signaling in MMP development. A vertebrate phylogeny and a hypothetical scenario of the participation of HGF/MET signaling in MMPs. A stem osteichthyan acquired Met expressions in MMPs and Hgf expressions in fin buds, and established the delamination (and possibly the migration) of fin MMPs by HGF/MET signaling. A mouse ancestor gained Hgf expressions in the migration route of HBM and evolved HGF/MET signal pathway in HBM development. HBM, hypobranchial muscle

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