Fig. 5
From: Hedgehog signaling controls mouth opening in the amphioxus
Hedgehog perturbation affects the size of amphioxus mouth. a, a1: Left lateral view of L1 stage larvae focused on the left-sided mouth opening in control embryos (black arrow), Scale bar, 100 μm. b, b1:Hh mRNA injection results in a dramatic increase in mouth size. c, c1: Smo-TALEN mRNA injection results in a small mouth in the amphioxus. d, d1: Smo gene knockout leads to a complete loss of mouth opening. Numbers in the top right corner of a panel show the number of times the phenotype was observed in the total number of embryos examined