Fig. 7
From: Bapx1 upregulation is associated with ectopic mandibular cartilage development in amphibians
Effect of Ly-294,002 treatment on the external and internal morphology of A. mexicanum. Dorsal view of a control and b Ly-294,002 treated specimens reveals no differences in external morphology. Lateral view of 3D-reconstructions based on confocal laser scanning microscopy of c control and d Ly-294,002 treated specimen shows the development of an ectopic cartilage lateral to the jaw articulation in treated specimens. The musculature of e control and f treated specimens are similar and no changes in origination or insertion of muscles can be observed after bapx1 upregulation. cm, Meckel’s cartilage; dm, M. depressor mandibulae; ec, ectopic cartilage; lma, M. levator mandibulae articularis; lme, M. levator mandibulae externus; lml, M. levator mandibulae longus; pq, palatoquadrate. Scale bar 500 μm