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Fig. 5 | Zoological Letters

Fig. 5

From: An approach for elucidating dermal fibroblast dedifferentiation in amphibian limb regeneration

Fig. 5

Gene expression patterns revealed by in situ hybridization. The blastema samples were prepared at 2 dpa (A–F), 5 dpa (G–L), and 10 dpa (M–R). A, G, M expression pattern of Adra2a. B, H, N expression pattern of Fblim1. C, I, O expression pattern of Loxl2. D, J, P expression pattern of Pde4b. E, K, Q expression pattern of Spry1. F, L, R expression pattern of Timp3. The upper panels (A–R) show the distal region of the amputated limbs. The lower panels (A’–R’) show the proximal or the approximate border of the amputation plane. The asterisks indicate the disconnection of the dermal collagen layer, suggesting the amputation plane. Scale bar in A = 400 μm

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